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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8BPO

Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A1)		28S ribosomal RNApolymer43801418701.61Oryctolagus cuniculus
2B
(B1)		5S ribosomal RNApolymer12038691.91GenBank (4CXE_4)Oryctolagus cuniculus (rabbit)
3C
(C1)		5.8S ribosomal RNApolymer15650143.61GenBank (4CXE_3)Oryctolagus cuniculus (rabbit)
4D
(D1)		Nascent polypeptide-associated complex subunit alpha N-terminal regionpolymer292526.11Oryctolagus cuniculus
5E
(A2)		60S ribosomal protein L8polymer25728088.91Oryctolagus cuniculus (rabbit)
6F
(B2)		Ribosomal protein L3polymer40346108.01UniProt (G1TL06)
Pfam (PF00297)		Oryctolagus cuniculus (rabbit)uL3
7G
(C2)		60S ribosomal protein L4polymer42547727.61UniProt (A0A5F9C3C5)
Pfam (PF00573)
Pfam (PF14374)		Oryctolagus cuniculus (rabbit)uL4
8H
(D2)		Ribosomal_L18_c domain-containing proteinpolymer29734481.81UniProt (G1SYJ6)
UniProt (by SIFTS) (P19949)		Oryctolagus cuniculus (rabbit)60S ribosomal protein L5
9I
(E2)		60S ribosomal protein L6polymer29133028.31UniProt (G1SKF7)
Pfam (PF03868)
Pfam (PF01159)		Oryctolagus cuniculus (rabbit)
10J
(F2)		60S ribosomal protein L7polymer24729201.81Oryctolagus cuniculus (rabbit)
11K
(G2)		60S ribosomal protein L7apolymer31936221.51UniProt (G1STW0)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)eL8
12L
(H2)		60S ribosomal protein L9polymer19221871.41UniProt (G1SWI6)
Pfam (PF00347)		Oryctolagus cuniculus (rabbit)uL6
13M
(I2)		Ribosomal protein L10polymer21424643.11UniProt (B7NZQ2)
Pfam (PF00252)		Oryctolagus cuniculus (rabbit)Ribosomal protein L10 (Predicted)
14N
(J2)		60S ribosomal protein L11polymer17820288.51UniProt (G1TUB8)
Pfam (PF00281)
Pfam (PF00673)		Oryctolagus cuniculus (rabbit)
15O
(K2)		60S ribosomal protein L13polymer21124331.71UniProt (G1TKB3)
Pfam (PF01294)		Oryctolagus cuniculus (rabbit)eL13
16P
(L2)		60S ribosomal protein L14polymer21823870.51UniProt (G1SZ12)
Pfam (PF01929)		Oryctolagus cuniculus (rabbit)
17Q
(M2)		Ribosomal protein L15polymer20424207.31UniProt (G1T0C1)
Pfam (PF00827)		Oryctolagus cuniculus (rabbit)
18R
(N2)		60S ribosomal protein L13apolymer20323533.31Oryctolagus cuniculus (rabbit)
19S
(O2)		60S ribosomal protein L17polymer18421444.21Oryctolagus cuniculus (rabbit)
20T
(P2)		Ribosomal protein L18polymer18721568.51Oryctolagus cuniculus (rabbit)
21U
(Q2)		60S ribosomal protein L19polymer19623535.31Oryctolagus cuniculus (rabbit)
22V
(R2)		60S ribosomal protein L18apolymer17620827.61Oryctolagus cuniculus (rabbit)
23W
(S2)		60S ribosomal protein L21polymer16018610.01UniProt (G1SHQ2)
Pfam (PF01157)		Oryctolagus cuniculus (rabbit)eL21
24X
(T2)		60S ribosomal protein L22polymer12814813.01Oryctolagus cuniculus (rabbit)
25Y
(U2)		60S ribosomal protein L23polymer14014892.51UniProt (G1T6D1)
Pfam (PF00238)		Oryctolagus cuniculus (rabbit)
26Z
(V2)		Ribosomal protein L24polymer15717825.11UniProt (G1SE28)
Pfam (PF01246)		Oryctolagus cuniculus (rabbit)eL24
27AA
(W2)		Ribosomal_L23eN domain-containing proteinpolymer15617768.21UniProt (G1SE76)
Pfam (PF03939)
Pfam (PF00276)		Oryctolagus cuniculus (rabbit)uL23
28BA
(X2)		Ribosomal protein L26polymer14517303.41UniProt (G1SQH0)
Pfam (PF16906)
Pfam (PF00467)		Oryctolagus cuniculus (rabbit)
29CA
(Y2)		60S ribosomal protein L27polymer13615835.81UniProt (G1TXF6)
Pfam (PF00467)
Pfam (PF01777)		Oryctolagus cuniculus (rabbit)
30DA
(Z2)		60S ribosomal protein L27apolymer14816620.61UniProt (G1SNY0)
Pfam (PF00828)		Oryctolagus cuniculus (rabbit)uL15
31EA
(a2)		60S ribosomal protein L29polymer22624931.61UniProt (G1SGR6)
Pfam (PF01779)		Oryctolagus cuniculus (rabbit)eL29
32FA
(b2)		60S ribosomal protein L30polymer11512807.11UniProt (G1TDL2)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)eL30
33GA
(c2)		60S ribosomal protein L31polymer12514494.91UniProt (G1SHG0)
Pfam (PF01198)		Oryctolagus cuniculus (rabbit)eL31
34HA
(d2)		Ribosomal protein L32polymer13515898.91UniProt (G1U437)
Pfam (PF01655)
UniProt (by SIFTS) (G1TUN8)		Oryctolagus cuniculus (rabbit)eL32
35IA
(e2)		60S ribosomal protein L35apolymer11012580.81UniProt (G1SF08)
Pfam (PF01247)		Oryctolagus cuniculus (rabbit)eL33
36JA
(f2)		60S ribosomal protein L34polymer11613196.91UniProt (G1U945)
Pfam (PF01199)
UniProt (by SIFTS) (G1TXG5)		Oryctolagus cuniculus (rabbit)eL34
37KA
(g2)		60S ribosomal protein L35polymer12214435.41UniProt (G1SIT5)
Pfam (PF00831)		Oryctolagus cuniculus (rabbit)uL29
38LA
(h2)		60S ribosomal protein L36polymer10512263.81UniProt (G1TTQ5)
Pfam (PF01158)		Oryctolagus cuniculus (rabbit)
39MA
(i2)		Ribosomal protein L37polymer9711111.01UniProt (U3KPD5)
Pfam (PF01907)		Oryctolagus cuniculus (rabbit)
40NA
(j2)		60S ribosomal protein L38polymer708238.91UniProt (G1U001)
Pfam (PF01781)		Oryctolagus cuniculus (rabbit)eL38
41OA
(k2)		60S ribosomal protein L39-likepolymer516455.81UniProt (G1TTN1)
Pfam (PF00832)		Oryctolagus cuniculus (rabbit)eL39
42PA
(l2)		Ubiquitin-60S ribosomal protein L40polymer10211699.81Oryctolagus cuniculus (rabbit)
43QA
(m2)		60S ribosomal protein L41polymer253473.51UniProt (A0A087WNH4)
Pfam (PF05162)		Oryctolagus cuniculus (rabbit)eL41
44RA
(n2)		60S ribosomal protein L36a-likepolymer10612477.01UniProt (G1U344)
Pfam (PF00935)
UniProt (by SIFTS) (G1T040)		Oryctolagus cuniculus (rabbit)eL42
45SA
(o2)		60S ribosomal protein L37apolymer9210299.41UniProt (G1SY53)
Pfam (PF01780)		Oryctolagus cuniculus (rabbit)eL43
46TA
(p2)		60S ribosomal protein L28polymer13715783.61UniProt (G1U7L1)
Pfam (PF01778)		Oryctolagus cuniculus (rabbit)eL28
47UA
(q2)		60S acidic ribosomal protein P0polymer31834380.51UniProt (G1SPK4)
Pfam (PF00466)
Pfam (PF17777)
Pfam (PF00428)		Oryctolagus cuniculus (rabbit)uL10
48VA
(r2)		60S ribosomal protein L12polymer16517847.61UniProt (G1SMR7)
Pfam (PF03946)
Pfam (PF00298)		Oryctolagus cuniculus (rabbit)
49WA
(s2)		S phase cyclin A-associated protein in the endoplasmic reticulumpolymer1411159795.51UniProt (Q9BY12)
Pfam (PF16501)
Pfam (PF12874)		Homo sapiens (human)S phase cyclin A-associated protein in the ER,Zinc finger protein 291,SCAPER
50XA
(t2)		Tetratricopeptide repeat protein 5polymer48954176.91UniProt (Q8N0Z6)
Pfam (PF16669)		Homo sapiens (human)TPR repeat protein 5,Stress-responsive activator of p300,Protein Strap,TTC5
51YA
(u2)		Tubulin beta chainpolymer647164.01UniProt (P07437)Homo sapiens (human)Tubulin beta-5 chain
52AB, AC, AD, AE, AF...
(A1, O2, U2, Z2, f2...)		MAGNESIUM IONnon-polymer24.3214Chemie (MG)
53EJ, GJ, HJ, IJ, JJ
(f2, i2, l2, n2, o2)		ZINC IONnon-polymer65.45Chemie (ZN)
Sequence modifications
G2: 1 - 319 (UniProt: G1STW0)
PDBExternal DatabaseDetails
Gly 244Cys 244conflict
K2: 1 - 211 (UniProt: G1TKB3)
PDBExternal DatabaseDetails
Arg 74His 74conflict
Arg 190His 190conflict
j2: 1 - 70 (UniProt: G1U001)
PDBExternal DatabaseDetails
Lys 24Asn 24conflict
s2: 1 - 1400 (UniProt: Q9BY12)
PDBExternal DatabaseDetails
Met -10-initiating methionine
Asp -9-expression tag
Tyr -8-expression tag
Lys -7-expression tag
Asp -6-expression tag
Asp -5-expression tag
Asp -4-expression tag
Asp -3-expression tag
Lys -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
t2: 1 - 440 (UniProt: Q8N0Z6)
PDBExternal DatabaseDetails
Met -48-initiating methionine
Gly -47-expression tag
His -46-expression tag
His -45-expression tag
His -44-expression tag
His -43-expression tag
His -42-expression tag
His -41-expression tag
Glu -40-expression tag
Asn -39-expression tag
Leu -38-expression tag
Tyr -37-expression tag
Phe -36-expression tag
Gln -35-expression tag
Gly -34-expression tag
Ser -33-expression tag
Ala -32-expression tag
Trp -31-expression tag
Ser -30-expression tag
His -29-expression tag
Pro -28-expression tag
Gln -27-expression tag
Phe -26-expression tag
Glu -25-expression tag
Lys -24-expression tag
Gly -23-expression tag
Gly -22-expression tag
Gly -21-expression tag
Ser -20-expression tag
Gly -19-expression tag
Gly -18-expression tag
Gly -17-expression tag
Ser -16-expression tag
Gly -15-expression tag
Gly -14-expression tag
Ser -13-expression tag
Ala -12-expression tag
Trp -11-expression tag
Ser -10-expression tag
His -9-expression tag
Pro -8-expression tag
Gln -7-expression tag
Phe -6-expression tag
Glu -5-expression tag
Lys -4-expression tag
Gly -3-expression tag
Ser -2-expression tag
Ser -1-expression tag
Gly 0-expression tag
u2: 1 - 60 (UniProt: P07437)
PDBExternal DatabaseDetails
Met 61-expression tag
Lys 62-expression tag
Leu 63-expression tag
Val 64-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains51
Total formula weight2622224.1
Non-Polymers*Number of molecules219
Total formula weight5528.3
All*Total formula weight2627752.5
*Water molecules are not included.

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PDB entries from 2024-10-30

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