8BO7
COAGULATION FACTOR XI PROTEASE DOMAIN IN COMPLEX WITH ACTIVE SITE INHIBITOR 34
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AAA) | Coagulation factor XIa light chain | polymer | 238 | 26856.5 | 1 | UniProt (P03951) Pfam (PF00089) | Homo sapiens (human) | |
| 2 | B (AAA) | 4-[[(2~{S})-2-[4-(5-chloranyl-2-cyano-phenyl)-3-methoxy-6-oxidanylidene-2,5-dihydropyridin-1-yl]-3-[(2~{S})-oxan-2-yl]propanoyl]amino]benzoic acid | non-polymer | 538.0 | 1 | Chemie (QW6) | |||
| 3 | C (AAA) | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 4 | D (AAA) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 5 | E (AAA) | water | water | 18.0 | 319 | Chemie (HOH) |
Sequence modifications
AAA: 388 - 625 (UniProt: P03951)
| PDB | External Database | Details |
|---|---|---|
| Ser 500 | Cys 500 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26856.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 852.3 | |
| All* | Total formula weight | 27708.8 |
