8BNT
The DH domain of ARHGEF2 bound to RhoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transforming protein RhoA | polymer | 185 | 20926.0 | 1 | UniProt (P61586) Pfam (PF00071) | Homo sapiens (human) | Rho cDNA clone 12,h12 |
| 2 | B (B) | Rho guanine nucleotide exchange factor 2 | polymer | 245 | 28644.2 | 1 | UniProt (Q92974) Pfam (PF00621) | Homo sapiens (human) | Guanine nucleotide exchange factor H1,GEF-H1,Microtubule-regulated Rho-GEF,Proliferating cell nucleolar antigen p40 |
| 3 | C, J, K, L, M (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 5 | Chemie (DMS) | |||
| 4 | D, E, F, G, H... (A, B) | FORMIC ACID | non-polymer | 46.0 | 15 | Chemie (FMT) | |||
| 5 | W, X (A, B) | water | water | 18.0 | 451 | Chemie (HOH) |
Sequence modifications
A: 1 - 184 (UniProt: P61586)
B: 206 - 448 (UniProt: Q92974)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 204 | - | expression tag |
| Met 205 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49570.1 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1081.0 | |
| All* | Total formula weight | 50651.2 |
