8BM5
Ternary structure of 14-3-3s, ERRg phosphopeptide and dual-reactive compound 7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26553.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (B) | Estrogen-related receptor gamma | polymer | 10 | 1215.4 | 1 | UniProt (P62508) | Homo sapiens | ERR gamma-2,Estrogen receptor-related protein 3,Nuclear receptor subfamily 3 group B member 3 |
| 3 | C, E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | G (A) | 4-methanoyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzenesulfonamide | non-polymer | 259.3 | 1 | Chemie (QQ0) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 323 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
B: 174 - 182 (UniProt: P62508)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asn 38 | Cys 38 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Nh2 183 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27769.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 367.7 | |
| All* | Total formula weight | 28137.0 |
