8BL8

Human serotonin 5-HT3A receptor (apo, active/distorted conformation)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (A, B, C, D, E)	5-hydroxytryptamine receptor 3A	polymer	397	46386.0	5	UniProt (P46098) Pfam (PF02931) Pfam (PF02932)	Homo sapiens (human)	5-HT3-A,5-HT3A,5-hydroxytryptamine receptor 3,5-HT-3,5-HT3R,Serotonin receptor 3A,Serotonin-gated ion channel receptor
2	F, G, H, I, J... (F, G, H, I, J...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	10	In PDB GlyTouCan (G42666HT)
3	P, Q, R, S, T (A, B, C, D, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)

Sequence modifications

A, B, C, D, E: 29 - 410 (UniProt: P46098)
A, B, C, D, E: 411 - 478 (UniProt: P46098)

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	231930.2
Branched	Number of molecules	10
	Total formula weight	4244.0
Non-Polymers*	Number of molecules	5
	Total formula weight	1106.0
All*	Total formula weight	237280.2

*Water molecules are not included.