8BK1
Mutant Imine Reductase IR007-143 from Amycolatopsis azurea, E120A, M197W, M206S, A213P, D238G, I240L
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Mutant Imine Reductase IR007-143 from Amycolatopsis azurea, E120A, M197W, M206S, A213P, D238G, I240L | polymer | 288 | 30913.1 | 4 | UniProt (M2QI47) Pfam (PF03446) Pfam (PF21761) | Amycolatopsis azurea | |
| 2 | E, I, L, O (A, B, C, D) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) | |||
| 3 | F, G, H, J, K... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 4 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 286 (UniProt: M2QI47)
| PDB | External Database | Details |
|---|---|---|
| Glu -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 120 | Glu 120 | engineered mutation |
| Trp 197 | Met 197 | engineered mutation |
| Ser 206 | Met 206 | engineered mutation |
| Pro 213 | Ala 213 | engineered mutation |
| Gly 238 | Asp 238 | engineered mutation |
| Leu 240 | Ile 240 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 123652.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3742.1 | |
| All* | Total formula weight | 127394.5 |






