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8BK1

Mutant Imine Reductase IR007-143 from Amycolatopsis azurea, E120A, M197W, M206S, A213P, D238G, I240L

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DMutant Imine Reductase IR007-143 from Amycolatopsis azurea, E120A, M197W, M206S, A213P, D238G, I240Lpolymer28830913.14UniProt (M2QI47)
Pfam (PF03446)
Pfam (PF21761)
In PDB
Amycolatopsis azurea
2A, B, C, DNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.44Chemie (NAP)
3A, B, C, DSULFATE IONnon-polymer96.18Chemie (SO4)
4waterwater18.0232Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 286 (UniProt: M2QI47)
PDBExternal DatabaseDetails
Glu -1-expression tag
Ser 0-expression tag
Ala 120Glu 120engineered mutation
Trp 197Met 197engineered mutation
Ser 206Met 206engineered mutation
Pro 213Ala 213engineered mutation
Gly 238Asp 238engineered mutation
Leu 240Ile 240engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight123652.3
Non-Polymers*Number of molecules12
Total formula weight3742.1
All*Total formula weight127394.5
*Water molecules are not included.

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PDB entries from 2024-07-10

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