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8BJF

Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (inward-facing conformation)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ATP-binding cassette sub-family C member 4polymer1325149693.91UniProt (O15439)
Pfam (PF00664)
Pfam (PF00005)
Homo sapiens (human)MRP/cMOAT-related ABC transporter,Multi-specific organic anion transporter B,MOAT-B,Multidrug resistance-associated protein 4
2B, F
(A)
CHOLESTEROLnon-polymer386.72Chemie (CLR)
3C, D, E, G
(A)
CHOLESTEROL HEMISUCCINATEnon-polymer486.74Chemie (Y01)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight149693.9
Non-Polymers*Number of molecules6
Total formula weight2720.2
All*Total formula weight152414.1
*Water molecules are not included.

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PDB entries from 2026-01-21

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