8BI9

Structure of a cyclic beta-hairpin peptide derived from neuronal nitric oxide synthase (T112W/T116E variant)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A, C, D	Nitric oxide synthase, brain	polymer	23	2601.8	4	UniProt (P29475) In PDB	Homo sapiens	Constitutive NOS,NC-NOS,NOS type I,Neuronal NOS,N-NOS,nNOS,Peptidyl-cysteine S-nitrosylase NOS1,bNOS
2	C	TERTIARY-BUTYL ALCOHOL	non-polymer		74.1	1	Chemie (TBU)
3		water	water		18.0	79	Chemie (HOH)

Sequence modifications

B, A, C, D: 1105 - 1125 (UniProt: P29475)

PDB	External Database	Details
Gln 1104	-	linker
Trp 1112	Thr 112	engineered mutation
Glu 1116	Thr 116	engineered mutation
Dpr 1125	Pro 125	engineered mutation
Gly 1126	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	10407.4
Non-Polymers*	Number of molecules	1
	Total formula weight	74.1
All*	Total formula weight	10481.5

*Water molecules are not included.