Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E | Gamma-aminobutyric acid receptor subunit alpha-5 | polymer | 361 | 41205.9 | 5 | UniProt (P31644) Pfam (PF02931) Pfam (PF02932) In PDB | Homo sapiens (human) | GABA(A) receptor subunit alpha-5 |
| 2 | C, A, D, B, E | SULFATE ION | non-polymer | 96.1 | 29 | Chemie (SO4) | |||
| 3 | C, A, D, E, B | ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate | non-polymer | 303.3 | 5 | Chemie (FYP) | |||
| 4 | C, A, D, B, E | Pregnanolone | non-polymer | 318.5 | 5 | Chemie (P9N) | |||
| 5 | C, A, D, B, E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 6 | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 315 (UniProt: P31644)
A, B, C, D, E: 393 - 419 (UniProt: P31644)
| PDB | External Database | Details |
|---|---|---|
| Met 48 | Ile 79 | conflict |
| Asn 51 | Thr 82 | conflict |
| Ile 67 | Val 98 | conflict |
| Ala 70 | Arg 101 | conflict |
| Thr 72 | Ser 103 | conflict |
| Asp 90 | Asn 121 | conflict |
| Arg 92 | Leu 123 | conflict |
| Val 93 | Leu 124 | conflict |
| Asp 95 | Ser 126 | conflict |
| Gln 96 | Lys 127 | conflict |
| Asp 107 | Gly 138 | conflict |
| Phe 111 | Ile 142 | conflict |
| Gly 114 | Asn 145 | conflict |
| Met 121 | Leu 152 | conflict |
| Ile 124 | Leu 155 | conflict |
| Trp 125 | Glu 156 | conflict |
| Asn 126 | Asp 157 | conflict |
| Arg 129 | Thr 160 | conflict |
| Val 130 | Leu 161 | conflict |
| Asp 145 | Gln 176 | conflict |
| Glu 153 | Ala 184 | conflict |
| Gln 154 | His 185 | conflict |
| Asn 155 | Ala 186 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 316 | - | linker |
| Gln 317 | - | linker |
| Pro 318 | - | linker |
| Ala 319 | - | linker |
| Arg 320 | - | linker |
| Ala 321 | - | linker |
| Ala 322 | - | linker |
| Ile 404 | Val 435 | engineered mutation |
| Arg 420 | - | expression tag |
| Gly 421 | - | expression tag |
| Thr 422 | - | expression tag |
| Thr 423 | - | expression tag |
| Glu 424 | - | expression tag |
| Thr 425 | - | expression tag |
| Ser 426 | - | expression tag |
| Gln 427 | - | expression tag |
| Val 428 | - | expression tag |
| Ala 429 | - | expression tag |
| Pro 430 | - | expression tag |
| Ala 431 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 206029.7 | |
| Non-Polymers* | Number of molecules | 45 |
| Total formula weight | 7222.0 | |
| All* | Total formula weight | 213251.7 |
