8BEM
STE20-like serine/threonine-protein kinase (SLK) in complex with Tivozanib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, D, G) | STE20-like serine/threonine-protein kinase | polymer | 303 | 34589.4 | 4 | UniProt (Q9H2G2) Pfam (PF00069) | Homo sapiens (human) | STE20-like kinase,hSLK,CTCL tumor antigen se20-9,STE20-related serine/threonine-protein kinase,STE20-related kinase,Serine/threonine-protein kinase 2 |
| 2 | E, G, H, J (A, B, D, G) | TIVOZANIB | non-polymer | 454.9 | 4 | Chemie (AV9) | |||
| 3 | F, I, K (A, D, G) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | L, M, N, O (A, B, D, G) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A, B, D, G: 19 - 319 (UniProt: Q9H2G2)
| PDB | External Database | Details |
|---|---|---|
| Ser 17 | - | expression tag |
| Met 18 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 138357.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2107.6 | |
| All* | Total formula weight | 140465.1 |
