8BEA
Crystal structure of SOS1-HRas-peptidomimetic10
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | R | GTPase HRas | polymer | 186 | 21046.6 | 1 | UniProt (P01112) Pfam (PF00071) In PDB | Homo sapiens (human) | H-Ras-1,Ha-Ras,Transforming protein p21,c-H-ras,p21ras |
2 | S | Son of sevenless homolog 1 | polymer | 507 | 59348.8 | 1 | UniProt (Q07889) Pfam (PF00618) Pfam (PF00617) In PDB | Homo sapiens (human) | SOS-1 |
3 | P | SOS1-HRas-peptidomimetic10 | polymer | 7 | 1096.2 | 1 | synthetic construct | ||
4 | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence modifications
R: 1 - 166 (UniProt: P01112)
S: 564 - 1049 (UniProt: Q07889)
PDB | External Database | Details |
---|---|---|
Met -19 | - | initiating methionine |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 543 | - | initiating methionine |
Gly 544 | - | expression tag |
Ser 545 | - | expression tag |
Ser 546 | - | expression tag |
His 547 | - | expression tag |
His 548 | - | expression tag |
His 549 | - | expression tag |
His 550 | - | expression tag |
His 551 | - | expression tag |
His 552 | - | expression tag |
Ser 553 | - | expression tag |
Ser 554 | - | expression tag |
Gly 555 | - | expression tag |
Leu 556 | - | expression tag |
Val 557 | - | expression tag |
Pro 558 | - | expression tag |
Arg 559 | - | expression tag |
Gly 560 | - | expression tag |
Ser 561 | - | expression tag |
His 562 | - | expression tag |
Met 563 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 81491.6 | |
All* | Total formula weight | 81491.6 |