8BDN
VCB in complex with compound 23
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, D, G, J) | Elongin-B | polymer | 104 | 11852.4 | 4 | UniProt (Q15370) Pfam (PF00240) | Homo sapiens (human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 2 | B, E, H, K (B, E, H, K) | Elongin-C | polymer | 97 | 10974.6 | 4 | UniProt (Q15369) Pfam (PF03931) | Homo sapiens (human) | EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Transcription elongation factor B polypeptide 1 |
| 3 | C, F, I, L (C, F, I, L) | von Hippel-Lindau disease tumor suppressor | polymer | 162 | 18806.3 | 4 | UniProt (P40337) Pfam (PF01847) Pfam (PF17211) | Homo sapiens (human) | Protein G7,pVHL |
| 4 | M, N, O, P (C, F, I, L) | (2~{R})-3-methyl-1-[(2~{S},4~{R})-2-[(5~{R})-5-methyl-5-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]-4~{H}-1,2,4-oxadiazol-3-yl]-4-oxidanyl-pyrrolidin-1-yl]-2-(3-methyl-1,2-oxazol-5-yl)butan-1-one | non-polymer | 509.6 | 4 | Chemie (QFR) | |||
| 5 | AA, BA, Q, R, S... (K, L, A, B, C...) | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
B, E, H, K: 17 - 112 (UniProt: Q15369)
C, F, I, L: 54 - 213 (UniProt: P40337)
| PDB | External Database | Details |
|---|---|---|
| Met 16 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Gly 52 | - | expression tag |
| Ser 53 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 166533.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2038.5 | |
| All* | Total formula weight | 168571.6 |
