8BCA
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 26
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | U5 small nuclear ribonucleoprotein 200 kDa helicase | polymer | 1747 | 199666.7 | 1 | UniProt (O75643) Pfam (PF00270) Pfam (PF00271) Pfam (PF02889) | Homo sapiens (human) | Activating signal cointegrator 1 complex subunit 3-like 1,BRR2 homolog,U5 snRNP-specific 200 kDa protein,U5-200KD |
| 2 | B (J) | Pre-mRNA-processing-splicing factor 8 | polymer | 263 | 30133.2 | 1 | UniProt (Q6P2Q9) Pfam (PF01398) Pfam (PF08084) | Homo sapiens (human) | 220 kDa U5 snRNP-specific protein,PRP8 homolog,Splicing factor Prp8,p220 |
| 3 | C, D (B) | 3-azanyl-~{N}-methyl-4-(methylamino)benzenesulfonamide | non-polymer | 215.3 | 2 | Chemie (Q96) | |||
| 4 | E, G, H, I, J... (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 5 | F (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | O, P (B, J) | water | water | 18.0 | 173 | Chemie (HOH) |
Sequence modifications
B: 394 - 2136 (UniProt: O75643)
J: 2064 - 2320 (UniProt: Q6P2Q9)
| PDB | External Database | Details |
|---|---|---|
| Gly 390 | - | expression tag |
| Ala 391 | - | expression tag |
| Glu 392 | - | expression tag |
| Phe 393 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 2058 | - | expression tag |
| Pro 2059 | - | expression tag |
| Leu 2060 | - | expression tag |
| Gly 2061 | - | expression tag |
| Ser 2062 | - | expression tag |
| Met 2063 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 229799.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1081.3 | |
| All* | Total formula weight | 230881.1 |
