8BA5
Crystal structure of the DNMT3A ADD domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA (cytosine-5)-methyltransferase 3A | polymer | 144 | 16311.7 | 1 | UniProt (Q9Y6K1) Pfam (PF17980) Pfam (PF21255) In PDB | Homo sapiens (human) | Dnmt3a,Cysteine methyltransferase DNMT3A,DNA methyltransferase HsaIIIA,DNA MTase HsaIIIA,M.HsaIIIA |
| 2 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence modifications
A: 476 - 614 (UniProt: Q9Y6K1)
| PDB | External Database | Details |
|---|---|---|
| Gly 471 | - | expression tag |
| Pro 472 | - | expression tag |
| Leu 473 | - | expression tag |
| Gly 474 | - | expression tag |
| Ser 475 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16311.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 344.7 | |
| All* | Total formula weight | 16656.4 |
