8BA0
Drosophila melanogaster complex I in the Twisted state (Dm2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NADH-ubiquinone oxidoreductase chain 3 | polymer | 117 | 13572.5 | 1 | UniProt (P18930) Pfam (PF00507) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase subunit 3 |
| 2 | B (B) | LD31474p | polymer | 182 | 20494.0 | 1 | UniProt (Q9VXK7) Pfam (PF01058) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) 20 kDa subunit,isoform A,isoform B,isoform C |
| 3 | C (C) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | polymer | 209 | 24435.6 | 1 | UniProt (Q9VZU4) Pfam (PF00329) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) 30 kDa subunit |
| 4 | D (D) | Complex I-49kD | polymer | 428 | 48738.0 | 1 | UniProt (Q9V4E0) Pfam (PF00346) | Drosophila melanogaster (fruit fly) | NADH-ubiquinone oxidoreductase 49 kDa subunit |
| 5 | E (E) | NADH dehydrogenase (Ubiquinone) 24 kDa subunit, isoform A | polymer | 214 | 23979.4 | 1 | UniProt (Q9VX36) Pfam (PF01257) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) 24 kDa subunit,isoform B |
| 6 | F (F) | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 439 | 48060.2 | 1 | UniProt (Q9VMI3) Pfam (PF01512) Pfam (PF22461) Pfam (PF10589) | Drosophila melanogaster (fruit fly) | |
| 7 | G (G) | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | polymer | 731 | 78724.3 | 1 | UniProt (Q94511) Pfam (PF10588) Pfam (PF22117) Pfam (PF22151) Pfam (PF00384) Pfam (PF09326) Pfam (PF13510) | Drosophila melanogaster (fruit fly) | Complex I-75kD,CI-75kD |
| 8 | H (H) | NADH-ubiquinone oxidoreductase chain 1 | polymer | 315 | 36383.5 | 1 | UniProt (C7DZL9) Pfam (PF00146) UniProt (by SIFTS) (P18929) | Drosophila melanogaster (fruit fly) | |
| 9 | I (I) | NADH dehydrogenase (ubiquinone) 23 kDa subunit | polymer | 186 | 21203.0 | 1 | UniProt (Q9VF27) Pfam (PF12838) | Drosophila melanogaster (fruit fly) | |
| 10 | J (J) | NADH-ubiquinone oxidoreductase chain 6 | polymer | 167 | 19309.6 | 1 | UniProt (P18933) Pfam (PF00499) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase subunit 6 |
| 11 | K (K) | NADH-ubiquinone oxidoreductase chain 4L | polymer | 93 | 11032.4 | 1 | UniProt (P18934) Pfam (PF00420) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase subunit 4L |
| 12 | L (L) | NADH-ubiquinone oxidoreductase chain 5 | polymer | 577 | 65777.9 | 1 | UniProt (C7DZL4) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455) UniProt (by SIFTS) (P18932) | Drosophila melanogaster (fruit fly) | |
| 13 | M (M) | NADH-ubiquinone oxidoreductase chain 4 | polymer | 446 | 51473.2 | 1 | UniProt (P18931) Pfam (PF01059) Pfam (PF00361) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase subunit 4 |
| 14 | N (N) | NADH-ubiquinone oxidoreductase chain 2 | polymer | 341 | 39839.9 | 1 | UniProt (P03896) Pfam (PF00361) Pfam (PF06444) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase subunit 2 |
| 15 | O (O) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | polymer | 368 | 42724.6 | 1 | UniProt (P91929) Pfam (PF01712) | Drosophila melanogaster (fruit fly) | Complex I-42kD,CI-42kD,NADH-ubiquinone oxidoreductase 42 kDa subunit |
| 16 | P (P) | NADH dehydrogenase (Ubiquinone) 39 kDa subunit, isoform A | polymer | 377 | 42994.2 | 1 | UniProt (A0A024E3A5) Pfam (PF01370) UniProt (by SIFTS) (Q9VPE2) | Drosophila melanogaster (fruit fly) | FI24283p1 |
| 17 | Q (Q) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | polymer | 130 | 14960.8 | 1 | UniProt (Q9VWI0) Pfam (PF04800) | Drosophila melanogaster (fruit fly) | |
| 18 | R (R) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | polymer | 89 | 10197.6 | 1 | UniProt (Q9VMU0) Pfam (PF10276) | Drosophila melanogaster (fruit fly) | |
| 19 | S, T (T, U) | Acyl carrier protein, mitochondrial | polymer | 152 | 17258.0 | 2 | UniProt (Q94519) Pfam (PF00550) | Drosophila melanogaster (fruit fly) | ACP,NADH-ubiquinone oxidoreductase 9.6 kDa subunit,NADH-ubiquinone oxidoreductase acyl-carrier subunit |
| 20 | U (V) | NADH dehydrogenase (Ubiquinone) 13 kDa B subunit | polymer | 118 | 13135.2 | 1 | UniProt (Q9VTB4) Pfam (PF04716) | Drosophila melanogaster (fruit fly) | RH11203p |
| 21 | V (W) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | polymer | 114 | 13805.1 | 1 | UniProt (Q7JZK1) Pfam (PF05347) | Drosophila melanogaster (fruit fly) | Complex I-B14,NADH-ubiquinone oxidoreductase B14 subunit |
| 22 | W (X) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | polymer | 174 | 19742.2 | 1 | UniProt (Q9W125) Pfam (PF06747) | Drosophila melanogaster (fruit fly) | |
| 23 | X (Y) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | polymer | 167 | 18101.7 | 1 | UniProt (Q7JYH3) | Drosophila melanogaster (fruit fly) | Complex I-B14.7,NADH-ubiquinone oxidoreductase subunit B14.7 |
| 24 | Y (Z) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | polymer | 146 | 16961.6 | 1 | UniProt (Q9W402) Pfam (PF06212) | Drosophila melanogaster (fruit fly) | |
| 25 | Z (a) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | polymer | 73 | 8588.0 | 1 | UniProt (A8DYC5) Pfam (PF15879) | Drosophila melanogaster (fruit fly) | Complex I-MWFE,NADH-ubiquinone oxidoreductase MWFE subunit |
| 26 | AA (b) | RH45008p | polymer | 66 | 7376.4 | 1 | UniProt (Q9W380) | Drosophila melanogaster (fruit fly) | Uncharacterized protein,isoform A,isoform B |
| 27 | BA (d) | NADH dehydrogenase [ubiquinone] 1 subunit C2 | polymer | 115 | 12794.6 | 1 | UniProt (Q9VQM2) Pfam (PF06374) | Drosophila melanogaster (fruit fly) | |
| 28 | CA (e) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | polymer | 100 | 11884.8 | 1 | UniProt (Q7K1C0) Pfam (PF10200) | Drosophila melanogaster (fruit fly) | Complex I-15 kDa,NADH-ubiquinone oxidoreductase 15 kDa subunit |
| 29 | DA (f) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | polymer | 56 | 6232.3 | 1 | UniProt (Q9W3N7) Pfam (PF08040) | Drosophila melanogaster (fruit fly) | Complex I-MNLL,NADH-ubiquinone oxidoreductase MNLL subunit |
| 30 | EA (g) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | polymer | 106 | 12287.6 | 1 | UniProt (Q9V3L7) Pfam (PF10183) | Drosophila melanogaster (fruit fly) | Complex I-ESSS,NADH-ubiquinone oxidoreductase ESSS subunit |
| 31 | FA (h) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | polymer | 145 | 17451.8 | 1 | UniProt (Q9VTU2) Pfam (PF09781) | Drosophila melanogaster (fruit fly) | Complex I-SGDH,NADH-ubiquinone oxidoreductase SGDH subunit |
| 32 | GA (i) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 | polymer | 161 | 18467.2 | 1 | UniProt (Q9V3W2) Pfam (PF09782) | Drosophila melanogaster (fruit fly) | Complex I-B17,NADH-ubiquinone oxidoreductase B17 subunit |
| 33 | HA (j) | GEO11417p1 | polymer | 59 | 6878.7 | 1 | UniProt (Q7PL91) Pfam (PF14813) | Drosophila melanogaster (fruit fly) | NADH dehydrogenase (Ubiquinone) AGGG subunit,isoform A,isoform B,RH18150p |
| 34 | IA (k) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | polymer | 84 | 9480.9 | 1 | UniProt (Q9W2E8) Pfam (PF08122) | Drosophila melanogaster (fruit fly) | Complex I-B12,NADH-ubiquinone oxidoreductase B12 subunit |
| 35 | JA (l) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | polymer | 144 | 16935.8 | 1 | UniProt (Q9W3X7) Pfam (PF05821) | Drosophila melanogaster (fruit fly) | Complex I-ASHI,NADH-ubiquinone oxidoreductase ASHI subunit |
| 36 | KA (m) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | polymer | 108 | 12612.4 | 1 | UniProt (Q6IDF5) Pfam (PF07225) | Drosophila melanogaster (fruit fly) | Complex I-B15,NADH-ubiquinone oxidoreductase B15 subunit |
| 37 | LA (n) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | polymer | 134 | 16285.5 | 1 | UniProt (Q9VJZ4) Pfam (PF05347) | Drosophila melanogaster (fruit fly) | |
| 38 | MA (o) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | polymer | 112 | 13388.5 | 1 | UniProt (Q9VXZ0) Pfam (PF05676) | Drosophila melanogaster (fruit fly) | |
| 39 | NA (p) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | polymer | 151 | 18050.5 | 1 | UniProt (Q9VQR2) Pfam (PF10249) | Drosophila melanogaster (fruit fly) | |
| 40 | OA (q) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | polymer | 135 | 15983.1 | 1 | UniProt (Q9VQD7) Pfam (PF05071) | Drosophila melanogaster (fruit fly) | |
| 41 | PA (r) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | polymer | 103 | 11562.1 | 1 | UniProt (O97418) Pfam (PF07347) | Drosophila melanogaster (fruit fly) | Complex I-B14.5a,NADH-ubiquinone oxidoreductase subunit B14.5a |
| 42 | QA (s) | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial | polymer | 62 | 6512.3 | 1 | UniProt (Q9VZ01) Pfam (PF15880) | Drosophila melanogaster (fruit fly) | Complex I-9kD,NADH-ubiquinone oxidoreductase 9 kDa subunit |
| 43 | AB, BB, RA, WA, XA... (I, B, F, G) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 6 | Chemie (SF4) | |||
| 44 | CB, KB, LB, MB, SA... (L, Y, B) | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 6 | Chemie (3PE) | |||
| 45 | UA, ZA (E, G) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 46 | VA (F) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 47 | DB, GB (M, P) | CARDIOLIPIN | non-polymer | 1464.0 | 2 | Chemie (CDL) | |||
| 48 | EB (O) | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (DGT) | |||
| 49 | FB (P) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 50 | HB (R) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 51 | IB, JB (T, U) | ~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{S})-3-oxidanyltetradecanethioate | non-polymer | 584.7 | 2 | Chemie (EHZ) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 43 |
| Total formula weight | 952934.6 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 12821.7 | |
| All* | Total formula weight | 965756.3 |
