8B4T
Human cathepsin B in complex with the carbamate inhibitor 7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cathepsin B | polymer | 255 | 27956.2 | 1 | UniProt (P07858) Pfam (PF00112) | Homo sapiens (human) | APP secretase,APPS,Cathepsin B1 |
| 2 | B (A) | (2S)-2-[[(2S)-2-[(4-chloranylphenoxy)carbonylamino]-3-cyclohexyl-propanoyl]amino]-3-phenyl-propanoic acid | non-polymer | 473.0 | 1 | Chemie (P9F) | |||
| 3 | C (A) | water | water | 18.0 | 231 | Chemie (HOH) |
Sequence modifications
A: 0 - 254 (UniProt: P07858)
| PDB | External Database | Details |
|---|---|---|
| Ala 115 | Ser 194 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27956.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 473.0 | |
| All* | Total formula weight | 28429.1 |
