8B2K
Ternary structure of 14-3-3s, RND3 phosphopeptide and dual-reactive compound 10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 14-3-3 protein sigma | polymer | 236 | 26553.9 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B | Rho-related GTP-binding protein RhoE | polymer | 14 | 1679.9 | 1 | UniProt (P61587) In PDB | Homo sapiens | Protein MemB,Rho family GTPase 3,Rho-related GTP-binding protein Rho8,Rnd3 |
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | B | 3-bromanyl-5-methanoyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzamide | non-polymer | 302.2 | 1 | Chemie (OQ3) | |||
| 6 | water | water | 18.0 | 324 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asn 38 | Cys 38 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28233.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 410.6 | |
| All* | Total formula weight | 28644.3 |
