8AZF
Crystal structure of K449E variant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa in complex with adenosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Adenosylhomocysteinase | polymer | 472 | 51735.0 | 2 | UniProt (B7V419) Pfam (PF05221) Pfam (PF00670) UniProt (by SIFTS) (Q9I685) | Pseudomonas aeruginosa PAO1 | S-adenosyl-L-homocysteine hydrolase,AdoHcyase |
| 2 | C, G (A, C) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | D, H (A, C) | ADENOSINE | non-polymer | 267.2 | 2 | Chemie (ADN) | |||
| 4 | E, I (A, C) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 5 | F, J (A, C) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 6 | K, L (A, C) | water | water | 18.0 | 1607 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 469 (UniProt: B7V419)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Glu 449 | Lys 449 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 103469.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2129.5 | |
| All* | Total formula weight | 105599.4 |
