8AWR
Structure of recombinant human beta-glucocerebrosidase in complex with L-carbaxylosyl chloride
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AAA) | Lysosomal acid glucosylceramidase | polymer | 497 | 55659.2 | 1 | UniProt (P04062) Pfam (PF02055) Pfam (PF17189) | Homo sapiens (human) | Lysosomal acid GCase,Acid beta-glucosidase,Alglucerase,Beta-glucocerebrosidase,Beta-GC,Cholesterol glucosyltransferase,SGTase,Cholesteryl-beta-glucosidase,D-glucosyl-N-acylsphingosine glucohydrolase,Imiglucerase |
| 2 | B (AcA) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 3 | C, D (AAA) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | BA, CA, DA, E, EA... (AAA) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 23 | Chemie (EDO) | |||
| 5 | AA, L (AAA) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | Y (AAA) | (1~{S},2~{R},3~{S},6~{S})-6-chloranylcyclohex-4-ene-1,2,3-triol | non-polymer | 164.6 | 1 | Chemie (OIZ) | |||
| 7 | Z (AAA) | (1~{S},2~{S},3~{S},4~{R})-cyclohexane-1,2,3,4-tetrol | non-polymer | 148.2 | 1 | Chemie (OJ6) | |||
| 8 | FA (AAA) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 9 | GA, HA (AAA) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 10 | IA (AAA) | water | water | 18.0 | 465 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 55659.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 748.7 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 2526.9 | |
| All* | Total formula weight | 58934.9 |
