8AVA
Leukotriene A4 hydrolase in complex with 4-(4-benzylphenyl)-oxazol-2-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Leukotriene A-4 hydrolase | polymer | 617 | 70192.9 | 1 | UniProt (P09960) Pfam (PF17900) Pfam (PF01433) Pfam (PF09127) | Homo sapiens (human) | LTA-4 hydrolase,Leukotriene A(4) hydrolase,Tripeptide aminopeptidase LTA4H |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D, E, F (A) | YTTERBIUM (III) ION | non-polymer | 173.0 | 4 | Chemie (YB) | |||
| 4 | G, H, I, M (A) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 5 | J, K (A) | IMIDAZOLE | non-polymer | 69.1 | 2 | Chemie (IMD) | |||
| 6 | L (A) | 4-[4-(phenylmethyl)phenyl]-1,3-oxazol-2-amine | non-polymer | 250.3 | 1 | Chemie (OVO) | |||
| 7 | N, O (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 8 | P (A) | water | water | 18.0 | 647 | Chemie (HOH) |
Sequence modifications
A: 1 - 610 (UniProt: P09960)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 70192.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1566.4 | |
| All* | Total formula weight | 71759.3 |
