8AV6
CryoEM structure of INO80 core nucleosome complex in closed grappler conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | RuvB-like helicase | polymer | 462 | 50451.8 | 3 | UniProt (G0RYI5) Pfam (PF06068) Pfam (PF17856) | Thermochaetoides thermophila | |
| 2 | D, E, F (D, E, F) | RuvB-like helicase | polymer | 488 | 53212.7 | 3 | UniProt (G0RYC2) Pfam (PF06068) Pfam (PF17856) | Thermochaetoides thermophila | |
| 3 | G (G) | Ino80 | polymer | 1856 | 210443.3 | 1 | Thermochaetoides thermophila | ||
| 4 | H (H) | PAPA-1 domain-containing protein | polymer | 492 | 53346.0 | 1 | UniProt (G0RY01) Pfam (PF04795) | Thermochaetoides thermophila | |
| 5 | I (I) | YL1_C domain-containing protein | polymer | 219 | 23127.5 | 1 | UniProt (G0S590) Pfam (PF08265) | Thermochaetoides thermophila | |
| 6 | J (J) | DASH complex subunit DAD4 | polymer | 769 | 87773.1 | 1 | UniProt (G0S589) Pfam (PF00022) | Thermochaetoides thermophila | Outer kinetochore protein DAD4 |
| 7 | K (K) | DNA | polymer | 227 | 69840.4 | 1 | DNA molecule | ||
| 8 | L (L) | DNA (208-MER) | polymer | 227 | 70347.8 | 1 | DNA molecule | ||
| 9 | M, Q (M, Q) | Histone H3.2 | polymer | 135 | 15289.9 | 2 | UniProt (Q71DI3) Pfam (PF00125) | Homo sapiens (human) | Histone H3/m,Histone H3/o |
| 10 | N, R (N, R) | Histone H4 | polymer | 102 | 11263.2 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 11 | O, S (O, S) | Histone H2A | polymer | 129 | 13990.3 | 2 | UniProt (A0A8C0K5D3) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P0C0S8) | Homo sapiens (human) | |
| 12 | P, T (P, T) | Histone H2B type 1-C/E/F/G/I | polymer | 125 | 13806.0 | 2 | UniProt (P62807) Pfam (PF00125) | Homo sapiens (human) | Histone H2B.1 A,Histone H2B.a,H2B/a,Histone H2B.g,H2B/g,Histone H2B.h,H2B/h,Histone H2B.k,H2B/k,Histone H2B.l,H2B/l |
| 13 | U, V, W, X, Y... (A, B, C, D, E...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 6 | Chemie (ADP) | |||
| 14 | AA (J) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 934570.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 3070.4 | |
| All* | Total formula weight | 937641.2 |
