8AUZ
Crystal structure of GSK3 beta (GSK3b) in complex with FL291.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycogen synthase kinase-3 beta | polymer | 365 | 41689.8 | 2 | UniProt (P49841) Pfam (PF00069) | Homo sapiens (human) | GSK-3 beta,Serine/threonine-protein kinase GSK3B |
| 2 | C, E (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D, F (A, B) | 8-morpholin-4-yl-2-pyridin-3-yl-[1,3]oxazolo[5,4-f]quinoxaline | non-polymer | 333.3 | 2 | Chemie (O9C) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 383 (UniProt: P49841)
| PDB | External Database | Details |
|---|---|---|
| Ala 384 | - | expression tag |
| His 385 | - | expression tag |
| His 386 | - | expression tag |
| His 387 | - | expression tag |
| His 388 | - | expression tag |
| His 389 | - | expression tag |
| His 390 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83379.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 858.8 | |
| All* | Total formula weight | 84238.3 |
