8ATY
Crystal structure of PPAR gamma (PPARG) in complex with JP85 (compound 1).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor gamma | polymer | 277 | 31667.8 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | B, C (A) | 2-[4-chloranyl-6-(5,6,7,8-tetrahydronaphthalen-1-ylamino)pyrimidin-2-yl]sulfanylethanoic acid | non-polymer | 349.8 | 2 | Chemie (O7O) | |||
| 3 | D, E, F, G, H (A) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 4 | I (A) | water | water | 18.0 | 155 | Chemie (HOH) |
Sequence modifications
A: 203 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31667.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1160.1 | |
| All* | Total formula weight | 32827.9 |
