8ASF
Crystal structure of Thrombin in complex with macrocycle T1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L, A | Thrombin light chain | polymer | 36 | 4096.5 | 2 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (human) | |
2 | H, B | Thrombin heavy chain | polymer | 259 | 29780.2 | 2 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (human) | |
3 | H, B | 5-chloranyl-~{N}-[[(9~{S},15~{R})-8,14,17-tris(oxidanylidene)-3,20-dithia-7,13,16-triazatetracyclo[20.2.2.1^{5,7}.1^{9,13}]octacosa-1(25),22(26),23-trien-15-yl]methyl]thiophene-2-carboxamide | non-polymer | 635.3 | 2 | Chemie (NWF) | |||
4 | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 67753.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1270.5 | |
All* | Total formula weight | 69024.0 |