8ASD

Structure of the SFTSV L protein stalled at late elongation [LATE-ELONGATION]

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RNA-directed RNA polymerase	polymer	2084	235698.5	1	UniProt (U3GU88) Pfam (PF15518) Pfam (PF12603) Pfam (PF04196) In PDB	SFTS virus AH12	Replicase,Transcriptase
2	T	RNA (5'-R(P*AP*AP*AP*AP*AP*AP*GP*AP*UP*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U)-3')	polymer	26	8386.0	1		SFTS virus AH12
3	G	RNA (5'-R(P*AP*CP*AP*CP*AP*AP*AP*GP*AP*CP*CP*GP*CP*CP*CP*AP*GP*AP*CP*CP*UP*UP*UP*UP*UP*U)-3')	polymer	26	8207.9	1		SFTS virus AH12
4	E, P	RNA (5'-R(P*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*GP*AP*UP*GP*A)-3')	polymer	20	6452.0	2		SFTS virus AH12
5	A	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
6	A	5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine	non-polymer		483.2	1	Chemie (2KH)
7		water	water		18.0	32	Chemie (HOH)

Sequence modifications

A: 1 - 2084 (UniProt: U3GU88)

PDB	External Database	Details
Ala 112	Asp 112	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	265196.4
Non-Polymers*	Number of molecules	4
	Total formula weight	556.1
All*	Total formula weight	265752.5

*Water molecules are not included.