8ASB
Structure of the SFTSV L protein stalled at early elongation with the endonuclease domain in a raised conformation [EARLY-ELONGATION-ENDO]
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | RNA-dependent RNA-polymerase L protein | polymer | 2084 | 235698.5 | 1 | UniProt (U3GU88) Pfam (PF15518) Pfam (PF12603) Pfam (PF04196) In PDB | SFTS virus AH12 | Replicase,Transcriptase |
| 2 | P | RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*GP*A)-3') | polymer | 20 | 6452.0 | 1 | SFTS virus AH12 | ||
| 3 | T | RNA (5'-R(P*UP*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U)-3') | polymer | 26 | 8386.0 | 1 | SFTS virus AH12 | ||
| 4 | G | RNA (5'-R(P*AP*CP*A)-3') | polymer | 26 | 8208.9 | 1 | SFTS virus AH12 | ||
| 5 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | A | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine | non-polymer | 483.2 | 1 | Chemie (2KH) |
Sequence modifications
A: 1 - 2084 (UniProt: U3GU88)
| PDB | External Database | Details |
|---|---|---|
| Ala 112 | Asp 112 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 258745.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 507.5 | |
| All* | Total formula weight | 259252.9 |
