8AS2
Structure of arrestin2 in complex with 4P CCR5 phosphopeptide and Fab30
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-arrestin-1 | polymer | 359 | 40319.3 | 1 | UniProt (P49407) Pfam (PF00339) Pfam (PF02752) | Homo sapiens (human) | Arrestin beta-1,Non-visual arrestin-2 |
| 2 | B (B) | C-C chemokine receptor type 5 | polymer | 22 | 2659.4 | 1 | UniProt (by SIFTS) (P51681) | Homo sapiens | |
| 3 | C (H) | Fab30 heavy chain | polymer | 233 | 25053.9 | 1 | Phage display vector pTDisp | ||
| 4 | D (L) | Fab30 light chain | polymer | 220 | 23992.7 | 1 | Phage display vector pTDisp |
Sequence modifications
A: 1 - 359 (UniProt: P49407)
| PDB | External Database | Details |
|---|---|---|
| Leu 150 | Cys 150 | engineered mutation |
| Val 242 | Cys 242 | engineered mutation |
| Val 251 | Cys 251 | engineered mutation |
| Ser 269 | Cys 269 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 92025.3 | |
| All* | Total formula weight | 92025.3 |
