8AQX
streptavidin mutant S112I with an iridium catalyst for CH activation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Streptavidin | polymer | 158 | 16464.9 | 4 | UniProt (P22629) Pfam (PF01382) | Streptomyces avidinii | |
| 2 | E, F, G, H (A, B, C, D) | tert-butyl 7'-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-1-chloranyl-2,3,4,5,6-pentamethyl-spiro[1$l^{8}-iridapentacyclo[2.2.0.0^{1,3}.0^{1,5}.0^{2,6}]hexane-1,2'-3-aza-1-azonia-2$l^{8}-iridatricyclo[6.3.1.0^{4,12}]dodeca-1(11),4,6,8(12),9-pentaene]-3'-carboxylate | non-polymer | 847.5 | 4 | Chemie (NOF) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 181 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 14 - 159 (UniProt: P22629)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Met 4 | - | expression tag |
| Thr 5 | - | expression tag |
| Gly 6 | - | expression tag |
| Gly 7 | - | expression tag |
| Gln 8 | - | expression tag |
| Gln 9 | - | expression tag |
| Met 10 | - | expression tag |
| Gly 11 | - | expression tag |
| Arg 12 | - | expression tag |
| Asp 13 | - | expression tag |
| Ile 112 | Ser 136 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 65859.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 3389.9 | |
| All* | Total formula weight | 69249.5 |
