8ANA
Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the 50S ribosomal subunit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (0) | 50S ribosomal protein L33 | polymer | 55 | 6388.6 | 1 | UniProt (A0A3S5YPG8) Pfam (PF00471) UniProt (by SIFTS) (P0A7N9) | Escherichia coli BW25113 | |
| 2 | B (1) | 50S ribosomal protein L34 | polymer | 46 | 5397.5 | 1 | UniProt (A0A8X6EVB8) Pfam (PF00468) UniProt (by SIFTS) (P0A7P5) | Escherichia coli BW25113 | |
| 3 | C (2) | 50S ribosomal protein L35 | polymer | 65 | 7313.0 | 1 | UniProt (A0A8S0FT45) Pfam (PF01632) UniProt (by SIFTS) (P0A7Q1) | Escherichia coli BW25113 | |
| 4 | D (3) | 50S ribosomal protein L36 | polymer | 38 | 4377.4 | 1 | UniProt (A0A2X1PTA3) Pfam (PF00444) UniProt (by SIFTS) (P0A7Q6) | Escherichia coli BW25113 | |
| 5 | E (4) | 50S ribosomal protein L31 | polymer | 70 | 7887.1 | 1 | UniProt (C3SIV2) Pfam (PF01197) UniProt (by SIFTS) (P0A7M9) | Escherichia coli BW25113 | |
| 6 | F (A) | Drosocin1 | polymer | 19 | 2204.6 | 1 | UniProt (B4MNS1) UniProt (by SIFTS) (P36193) | Drosophila melanogaster | |
| 7 | G (a) | 23S ribosomal RNA | polymer | 2903 | 941463.4 | 1 | Escherichia coli BW25113 | ||
| 8 | H (b) | 5S ribosomal RNA | polymer | 120 | 38790.1 | 1 | Escherichia coli BW25113 | ||
| 9 | I (c) | 50S ribosomal protein L2 | polymer | 273 | 29923.6 | 1 | UniProt (A0A7L6YWH1) Pfam (PF00181) Pfam (PF03947) UniProt (by SIFTS) (P60422) | Escherichia coli BW25113 | |
| 10 | J (d) | 50S ribosomal protein L3 | polymer | 209 | 22291.6 | 1 | UniProt (C3SQU2) Pfam (PF00297) UniProt (by SIFTS) (P60438) | Escherichia coli BW25113 | |
| 11 | K (e) | 50S ribosomal protein L4 | polymer | 201 | 22121.6 | 1 | UniProt (D8A1N0) Pfam (PF00573) UniProt (by SIFTS) (P60723) | Escherichia coli BW25113 | |
| 12 | L (f) | 50S ribosomal protein L5 | polymer | 179 | 20333.6 | 1 | UniProt (D6IEK6) Pfam (PF00281) Pfam (PF00673) UniProt (by SIFTS) (P62399) | Escherichia coli BW25113 | |
| 13 | M (g) | 50S ribosomal protein L6 | polymer | 177 | 18932.8 | 1 | UniProt (C3SR17) Pfam (PF00347) UniProt (by SIFTS) (P0AG55) | Escherichia coli BW25113 | |
| 14 | N (h) | 50S ribosomal protein L9 | polymer | 149 | 15789.0 | 1 | UniProt (C3SFP2) Pfam (PF01281) Pfam (PF03948) UniProt (by SIFTS) (P0A7R1) | Escherichia coli BW25113 | |
| 15 | O (i) | 50S ribosomal protein L13 | polymer | 142 | 16050.6 | 1 | UniProt (A0A656YGQ7) Pfam (PF00572) UniProt (by SIFTS) (P0AA10) | Escherichia coli BW25113 | |
| 16 | P (j) | 50S ribosomal protein L14 | polymer | 123 | 13565.1 | 1 | UniProt (C3SQZ2) Pfam (PF00238) UniProt (by SIFTS) (P0ADY3) | Escherichia coli BW25113 | |
| 17 | Q (k) | 50S ribosomal protein L15 | polymer | 144 | 15008.5 | 1 | UniProt (P02413) Pfam (PF00828) | Escherichia coli BW25113 | Large ribosomal subunit protein uL15 |
| 18 | R (l) | 50S ribosomal protein L16 | polymer | 136 | 15312.3 | 1 | UniProt (A0A0H3EMH6) Pfam (PF00252) UniProt (by SIFTS) (P0ADY7) | Escherichia coli BW25113 | |
| 19 | S (m) | 50S ribosomal protein L17 | polymer | 127 | 14393.7 | 1 | UniProt (A0A1X3JBW6) Pfam (PF01196) UniProt (by SIFTS) (P0AG44) | Escherichia coli BW25113 | |
| 20 | T (n) | 50S ribosomal protein L18 | polymer | 117 | 12794.7 | 1 | UniProt (A0A514EKV0) Pfam (PF00861) UniProt (by SIFTS) (P0C018) | Escherichia coli BW25113 | |
| 21 | U (o) | 50S ribosomal protein L19 | polymer | 115 | 13159.3 | 1 | UniProt (A0A370V6W8) Pfam (PF01245) UniProt (by SIFTS) (P0A7K6) | Escherichia coli BW25113 | |
| 22 | V (p) | 50S ribosomal protein L20 | polymer | 118 | 13528.0 | 1 | UniProt (A0A378BCJ4) Pfam (PF00453) UniProt (by SIFTS) (P0A7L3) | Escherichia coli BW25113 | |
| 23 | W (q) | 50S ribosomal protein L21 | polymer | 103 | 11586.4 | 1 | UniProt (A0A0E2L2H1) Pfam (PF00829) UniProt (by SIFTS) (P0AG48) | Escherichia coli BW25113 | |
| 24 | X (r) | 50S ribosomal protein L22 | polymer | 110 | 12253.4 | 1 | UniProt (A0A0F6B7N1) Pfam (PF00237) UniProt (by SIFTS) (P61175) | Escherichia coli BW25113 | |
| 25 | Y (s) | 50S ribosomal protein L23 | polymer | 100 | 11222.2 | 1 | UniProt (D7Y3D8) Pfam (PF00276) UniProt (by SIFTS) (P0ADZ0) | Escherichia coli BW25113 | |
| 26 | Z (t) | 50S ribosomal protein L24 | polymer | 104 | 11339.3 | 1 | UniProt (S1E9P3) Pfam (PF00467) Pfam (PF17136) UniProt (by SIFTS) (P60624) | Escherichia coli BW25113 | |
| 27 | AA (u) | 50S ribosomal protein L25 | polymer | 94 | 10713.5 | 1 | UniProt (P68919) Pfam (PF01386) | Escherichia coli BW25113 | Large ribosomal subunit protein bL25 |
| 28 | BA (v) | 50S ribosomal protein L27 | polymer | 85 | 9146.5 | 1 | UniProt (C3SSG7) Pfam (PF01016) UniProt (by SIFTS) (P0A7L8) | Escherichia coli BW25113 | |
| 29 | CA (w) | 50S ribosomal protein L28 | polymer | 78 | 9027.6 | 1 | UniProt (C3SME2) Pfam (PF00830) UniProt (by SIFTS) (P0A7M2) | Escherichia coli BW25113 | |
| 30 | DA (x) | 50S ribosomal protein L29 | polymer | 63 | 7286.5 | 1 | UniProt (P0A7M6) Pfam (PF00831) | Escherichia coli BW25113 | Large ribosomal subunit protein uL29 |
| 31 | EA (y) | 50S ribosomal protein L30 | polymer | 59 | 6554.8 | 1 | UniProt (C3SR32) Pfam (PF00327) UniProt (by SIFTS) (P0AG51) | Escherichia coli BW25113 | |
| 32 | FA (z) | 50S ribosomal protein L32 | polymer | 57 | 6463.4 | 1 | UniProt (A0A657HW13) Pfam (PF01783) UniProt (by SIFTS) (P0A7N4) | Escherichia coli BW25113 | |
| 33 | GA, HA (3, 4) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 34 | IA (A) | 2-acetamido-2-deoxy-alpha-D-galactopyranose | non-polymer | 221.2 | 1 | Chemie (A2G) | |||
| 35 | AB, AC, AD, AE, AF... (a, b, c, d, z) | MAGNESIUM ION | non-polymer | 24.3 | 216 | Chemie (MG) | |||
| 36 | JI (a) | SPERMINE | non-polymer | 202.3 | 1 | Chemie (SPM) | |||
| 37 | SI, TI, UI, VI (A, a, e, r) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 32 |
| Total formula weight | 1352619.3 | |
| Non-Polymers* | Number of molecules | 220 |
| Total formula weight | 5804.2 | |
| All* | Total formula weight | 1358423.6 |
