8ALZ
Cryo-EM structure of ASCC3 in complex with ASC1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Activating signal cointegrator 1 | polymer | 585 | 66650.7 | 1 | UniProt (Q15650) Pfam (PF23135) Pfam (PF06221) Pfam (PF23134) Pfam (PF04266) | Homo sapiens (human) | ASC-1,Thyroid receptor-interacting protein 4,TR-interacting protein 4,TRIP-4 |
| 2 | B (B) | Activating signal cointegrator 1 complex subunit 3 | polymer | 1806 | 206276.1 | 1 | UniProt (Q8N3C0) Pfam (PF00271) Pfam (PF23445) Pfam (PF02889) Pfam (PF00270) | Homo sapiens (human) | ASC-1 complex subunit p200,ASC1p200,Helicase,ATP binding 1,Trip4 complex subunit p200 |
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A: 1 - 581 (UniProt: Q15650)
B: 401 - 2202 (UniProt: Q8N3C0)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 397 | - | expression tag |
| Ala 398 | - | expression tag |
| Glu 399 | - | expression tag |
| Phe 400 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 272926.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 273057.6 |
