8ALQ

The Solution Structure of the Triple Mutant Methyl-CpG-Binding Domain from MeCP2 that Binds to Asymmetrically Modified DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Methyl-CpG-binding protein 2	polymer	104	11905.3	1	UniProt (A0A8C5LDB3) Pfam (PF01429) UniProt (by SIFTS) (P51608) In PDB	Homo sapiens (human)	MeCp-2 protein,MeCp2

Sequence modifications

A: 3 - 95 (UniProt: A0A8C5LDB3)

PDB	External Database	Details
Ser 1	-	expression tag
Leu 2	-	expression tag
Glu 3	Arg 101	conflict
Thr 23	Lys 121	conflict
Ala 36	Val 134	conflict
Asn 48	Ser 146	conflict
Lys 85	Arg 183	conflict
Pro 87	Ala 185	conflict
Thr 96	-	expression tag
Ser 97	-	expression tag
His 98	-	expression tag
His 99	-	expression tag
His 100	-	expression tag
His 101	-	expression tag
His 102	-	expression tag
His 103	-	expression tag
His 104	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	11905.3
All*	Total formula weight	11905.3

*Water molecules are not included.