8ALO

Heterodimer formation of sensory domains of Vibrio cholerae regulators ToxR and ToxS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Cholera toxin transcriptional activator	polymer	106	11649.1	1	UniProt (P15795)	Vibrio cholerae
2	B (B)	Transmembrane regulatory protein ToxS	polymer	164	18681.8	1	UniProt (P24003) Pfam (PF17323)	Vibrio cholerae
3	C, D (A, B)	water	water		18.0	11	Chemie (HOH)

Sequence modifications

A: 201 - 294 (UniProt: P15795)

PDB	External Database	Details
Met 189	-	initiating methionine
Arg 190	-	expression tag
Gly 191	-	expression tag
Ser 192	-	expression tag
His 193	-	expression tag
His 194	-	expression tag
His 195	-	expression tag
His 196	-	expression tag
His 197	-	expression tag
His 198	-	expression tag
Gly 199	-	expression tag
Ser 200	-	expression tag

B: 25 - 173 (UniProt: P24003)

PDB	External Database	Details
Met 10	-	initiating methionine
Gly 11	-	expression tag
Ser 12	-	expression tag
Ser 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
Ser 20	-	expression tag
Gln 21	-	expression tag
Asp 22	-	expression tag
Pro 23	-	expression tag
Asn 24	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30330.9
All*	Total formula weight	30330.9

*Water molecules are not included.