8AHW
Structure of DCS-resistant variant D322N of alanine racemase from Mycobacterium tuberculosis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alanine racemase | polymer | 387 | 41278.0 | 2 | UniProt (P9WQA9) Pfam (PF01168) Pfam (PF00842) | Mycobacterium tuberculosis H37Rv | |
| 2 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | D, E, F, G, H (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 281 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 386 (UniProt: P9WQA9)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| His 2 | - | expression tag |
| Asn 322 | Asp 322 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82556.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 402.4 | |
| All* | Total formula weight | 82958.4 |
