8AHG
PAC-FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase PAK 4 | polymer | 297 | 33380.7 | 1 | UniProt (O96013) Pfam (PF00069) In PDB | Homo sapiens (human) | p21-activated kinase 4,PAK-4 |
| 2 | A | ~{N}-methyl-3-propan-2-yl-1~{H}-pyrazolo[3,4-c]pyridine-4-carboxamide | non-polymer | 218.3 | 1 | Chemie (M4I) | |||
| 3 | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence modifications
A: 300 - 591 (UniProt: O96013)
| PDB | External Database | Details |
|---|---|---|
| Gly 295 | - | expression tag |
| Pro 296 | - | expression tag |
| Leu 297 | - | expression tag |
| Gly 298 | - | expression tag |
| Ser 299 | - | expression tag |
| Ala 310 | Leu 310 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33380.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 218.3 | |
| All* | Total formula weight | 33599.0 |
