8AG5

Vaccinia C16 protein bound to Ku70/Ku80

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Ku70-Xrcc6	polymer	651	74234.7	1	UniProt (P12956) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF02037) In PDB	Homo sapiens (human)
2	B	X-ray repair cross-complementing protein 5	polymer	755	85546.5	1	UniProt (P13010) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF08785) In PDB	Homo sapiens (human)	86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit,CTC85,CTCBF,DNA repair protein XRCC5,Ku80,Ku86,Lupus Ku autoantigen protein p86,Nuclear factor IV,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
3	C, D	Protein C10	polymer	369	42476.7	2	UniProt (P03296) Pfam (PF03336) In PDB	Vaccinia virus Western Reserve

Sequence modifications

A: 1 - 609 (UniProt: P12956)

PDB	External Database	Details
Met -41	-	initiating methionine
Ser -40	-	expression tag
Ala -39	-	expression tag
Trp -38	-	expression tag
Ser -37	-	expression tag
His -36	-	expression tag
Pro -35	-	expression tag
Gln -34	-	expression tag
Phe -33	-	expression tag
Glu -32	-	expression tag
Lys -31	-	expression tag
Gly -30	-	expression tag
Ser -29	-	expression tag
Ala -28	-	expression tag
Gly -27	-	expression tag
Ser -26	-	expression tag
Ala -25	-	expression tag
Ala -24	-	expression tag
Gly -23	-	expression tag
Ser -22	-	expression tag
Gly -21	-	expression tag
Ala -20	-	expression tag
Gly -19	-	expression tag
Trp -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
Pro -15	-	expression tag
Gln -14	-	expression tag
Phe -13	-	expression tag
Glu -12	-	expression tag
Lys -11	-	expression tag
Leu -10	-	expression tag
Glu -9	-	expression tag
Val -8	-	expression tag
Leu -7	-	expression tag
Phe -6	-	expression tag
Gln -5	-	expression tag
Gly -4	-	expression tag
Pro -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B: 1 - 732 (UniProt: P13010)

PDB	External Database	Details
Met -22	-	initiating methionine
Ala -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Gly -10	-	expression tag
Ala -9	-	expression tag
Leu -8	-	expression tag
Glu -7	-	expression tag
Val -6	-	expression tag
Leu -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Gly -2	-	expression tag
Pro -1	-	expression tag
His 0	-	expression tag

C, D: 1 - 331 (UniProt: P03296)

PDB	External Database	Details
Gly 332	-	expression tag
Gly 333	-	expression tag
Glu 334	-	expression tag
Asn 335	-	expression tag
Leu 336	-	expression tag
Tyr 337	-	expression tag
Phe 338	-	expression tag
Gln 339	-	expression tag
Gly 340	-	expression tag
Trp 341	-	expression tag
Ser 342	-	expression tag
His 343	-	expression tag
Pro 344	-	expression tag
Gln 345	-	expression tag
Phe 346	-	expression tag
Glu 347	-	expression tag
Lys 348	-	expression tag
Gly 349	-	expression tag
Gly 350	-	expression tag
Gly 351	-	expression tag
Ser 352	-	expression tag
Gly 353	-	expression tag
Gly 354	-	expression tag
Gly 355	-	expression tag
Ser 356	-	expression tag
Gly 357	-	expression tag
Gly 358	-	expression tag
Ser 359	-	expression tag
Ser 360	-	expression tag
Ala 361	-	expression tag
Trp 362	-	expression tag
Ser 363	-	expression tag
His 364	-	expression tag
Pro 365	-	expression tag
Gln 366	-	expression tag
Phe 367	-	expression tag
Glu 368	-	expression tag
Lys 369	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	244734.5
All*	Total formula weight	244734.5

*Water molecules are not included.