8AEN

Human acetylcholinesterase in complex with zinc and N,N,N-trimethyl-2-oxo-2-(2-(pyridin-2-ylmethylene)hydrazineyl)ethan-1-aminium

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Acetylcholinesterase	polymer	543	59576.2	2	UniProt (P22303) Pfam (PF00135) In PDB	Homo sapiens (human)	AChE
2	C, F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	2	In PDB GlyTouCan (G21290RB)
3	D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	E	N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		674.6	1	In PDB GlyTouCan (G00065MO)
5	A, B	N,N,N-trimethyl-2-oxo-2-(2-(pyridin-2-ylmethylene)hydrazineyl)ethan-1-aminium	non-polymer		221.3	2	Chemie (LWL)
6	A, B	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
7	B, A	SULFATE ION	non-polymer		96.1	21	Chemie (SO4)
8	A, B	CHLORIDE ION	non-polymer		35.5	36	Chemie (CL)
9	B, A	MAGNESIUM ION	non-polymer		24.3	12	Chemie (MG)
10		water	water		18.0	136	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	119152.4
Branched	Number of molecules	4
	Total formula weight	2240.1
Non-Polymers*	Number of molecules	75
	Total formula weight	4289.5
All*	Total formula weight	125682.0

*Water molecules are not included.