8AE7
The strucuture of Compound 15 bound to CK2alpha
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Casein kinase II subunit alpha | polymer | 328 | 39031.4 | 1 | UniProt (P68400) Pfam (PF00069) In PDB | Homo sapiens (human) | CK II alpha |
2 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
3 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
4 | A | 2-[5,6-bis(bromanyl)-1H-indazol-3-yl]ethanenitrile | non-polymer | 315.0 | 1 | Chemie (LVU) | |||
5 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
6 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
7 | water | water | 18.0 | 339 | Chemie (HOH) |
Sequence modifications
A: 2 - 329 (UniProt: P68400)
PDB | External Database | Details |
---|---|---|
Ser 21 | Arg 21 | engineered mutation |
Ala 74 | Lys 74 | engineered mutation |
Ala 75 | Lys 75 | engineered mutation |
Ala 76 | Lys 76 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 39031.4 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 917.6 | |
All* | Total formula weight | 39949.0 |