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8AE3

Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
IgM C2-domain from mousepolymer11712769.62Homo sapiens (human)
2C, E
(L, S)
IgM Fab, light chainpolymer21523367.92Homo sapiens (human)
3D, F
(H, Q)
IgM Fab, heavy chainpolymer22624574.72Homo sapiens (human)
4G, H, I, J, K...
(N, O, C, D, E...)
Immunoglobulin heavy constant mupolymer38341875.810Pfam (PF07654)
UniProt (by SIFTS) (P01871)
Homo sapiens (human)
5Q
(J)
Immunoglobulin J chainpolymer13615483.31Pfam (PF15097)
UniProt (by SIFTS) (P01591)
Homo sapiens (human)
6R, S, T
(I, M, P)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.43In PDB
GlyTouCan (G42666HT)
7AA, BA, CA, DA, U...
(G, R, K, T, N...)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.210Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains17
Total formula weight555665.4
BranchedNumber of molecules3
Total formula weight1273.2
Non-Polymers*Number of molecules10
Total formula weight2212.1
All*Total formula weight559150.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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