8ADT
Rational design of a calcium-independent trypsin variant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine protease 1 | polymer | 223 | 23256.3 | 1 | UniProt (P00760) Pfam (PF00089) In PDB | Bos taurus (cattle) | Anionic trypsin I,Anionic trypsin-I,Beta-trypsin,Cationic trypsin,Pretrypsinogen I,Trypsin I,Trypsin-I |
| 2 | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
A: 16 - 245 (UniProt: P00760)
| PDB | External Database | Details |
|---|---|---|
| Cys 70 | Glu 75 | engineered mutation |
| Cys 80 | Glu 85 | engineered mutation |
| Ala 195 | Ser 200 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23256.3 | |
| All* | Total formula weight | 23256.3 |
