8A5X

Crystal structure of phosphatidyl inositol 4-kinase II beta in complex with MM1373

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Phosphatidylinositol 4-kinase type 2-beta,Endolysin	polymer	514	59367.9	1	UniProt (Q8TCG2) UniProt (P00720) Pfam (PF00454) Pfam (PF00959) In PDB	Homo sapiens (human)	Phosphatidylinositol 4-kinase type II-beta,PI4KII-BETA,Lysis protein,Lysozyme,Muramidase
2	A	4-azanyl-7-[3-(hydroxymethyl)phenyl]quinazoline-6-carboxamide	non-polymer		294.3	1	Chemie (L6A)
3		water	water		18.0	106	Chemie (HOH)

Sequence modifications

A: 90 - 165 (UniProt: Q8TCG2)
A: 1001 - 1163 (UniProt: P00720)

PDB	External Database	Details
Gly 1011	Arg 12	engineered mutation
Thr 1053	Cys 54	engineered mutation
Ala 1096	Cys 97	engineered mutation
Arg 1136	Ile 137	engineered mutation

A: 176 - 450 (UniProt: Q8TCG2)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	59367.9
Non-Polymers*	Number of molecules	1
	Total formula weight	294.3
All*	Total formula weight	59662.2

*Water molecules are not included.