8A5U

Crystal structure of the beta3 subunit extracellular domain of nicotinic acetylcholine receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Neuronal acetylcholine receptor subunit beta-3	polymer	221	26007.2	1	UniProt (Q05901) Pfam (PF02931)	Homo sapiens (human)
2	B, C (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
3	D (B)	BICINE	non-polymer		163.2	1	Chemie (BCN)
4	E (B)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5	F (B)	water	water		18.0	49	Chemie (HOH)

Sequence modifications

B: 1 - 207 (UniProt: Q05901)

PDB	External Database	Details
Asp -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag
Tyr 135	Phe 159	engineered mutation
His 208	-	expression tag
His 209	-	expression tag
His 210	-	expression tag
His 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	26007.2
Non-Polymers*	Number of molecules	4
	Total formula weight	667.7
All*	Total formula weight	26674.9

*Water molecules are not included.