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8A34

MTH1 in complex with TH013071

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
7,8-dihydro-8-oxoguanine triphosphatasepolymer15918253.72UniProt (P36639)
Pfam (PF00293)
Homo sapiens (human)2-hydroxy-dATP diphosphatase,8-oxo-dGTPase,Nucleoside diphosphate-linked moiety X motif 1,Nudix motif 1
2C, H
(A, B)
5-(2-phenylphenyl)-1H-pyrimidine-2,4-dionenon-polymer264.32Chemie (KYI)
3D
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
4E, F, G, I, J...
(A, B)
SULFATE IONnon-polymer96.16Chemie (SO4)
5L, M
(A, B)
waterwater18.0108Chemie (HOH)
Sequence modifications
A, B: 1 - 156 (UniProt: P36639)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight36507.5
Non-Polymers*Number of molecules9
Total formula weight1164.0
All*Total formula weight37671.5
*Water molecules are not included.

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PDB entries from 2024-12-25

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