8A0N
Crystal structure of Candida auris dihydrofolate reductase complexed with NADPH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Dihydrofolate reductase | polymer | 213 | 24571.3 | 1 | UniProt (A0A0L0P1H8) Pfam (PF00186) | [Candida] auris | |
| 2 | B (B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 3 | C, D (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E (B) | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
| 5 | F (B) | water | water | 18.0 | 391 | Chemie (HOH) |
Sequence modifications
B: 0 - 203 (UniProt: A0A0L0P1H8)
| PDB | External Database | Details |
|---|---|---|
| Gly -9 | - | expression tag |
| Leu -8 | - | expression tag |
| Val -7 | - | expression tag |
| Pro -6 | - | expression tag |
| Arg -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| His -2 | - | expression tag |
| Met -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24571.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 931.6 | |
| All* | Total formula weight | 25502.8 |
