8A07

MTH1 in complex with TH001969

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	7,8-dihydro-8-oxoguanine triphosphatase	polymer	159	18253.7	2	UniProt (P36639) Pfam (PF00293) In PDB	Homo sapiens (human)	2-hydroxy-dATP diphosphatase,8-oxo-dGTPase,Nucleoside diphosphate-linked moiety X motif 1,Nudix motif 1
2	A, B	1~{H}-quinazoline-2,4-dione	non-polymer		162.1	2	Chemie (L3N)
3	A, B	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
4		water	water		18.0	122	Chemie (HOH)

Sequence modifications

A, B: 1 - 156 (UniProt: P36639)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	36507.5
Non-Polymers*	Number of molecules	7
	Total formula weight	804.6
All*	Total formula weight	37312.1

*Water molecules are not included.