7ZZ8
Cryo-EM structure of Lactococcus lactis pyruvate carboxylase with acetyl-CoA and cyclic di-AMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyruvate carboxylase | polymer | 1143 | 127349.6 | 4 | UniProt (A0A2A9IR05) | Lactococcus lactis | |
| 2 | BA, E, H, L, O... (D, A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 3 | F, M, T, Z (A, B, C, D) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 4 | AA, G, N, U (D, A, B, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
| 5 | CA, I, P, W (D, A, B, C) | ACETYL COENZYME *A | non-polymer | 809.6 | 4 | Chemie (ACO) | |||
| 6 | DA, J, Q, X (D, A, B, C) | PYRUVIC ACID | non-polymer | 88.1 | 4 | Chemie (PYR) | |||
| 7 | K, R (A, C) | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide | non-polymer | 658.4 | 2 | Chemie (2BA) | |||
| 8 | EA, FA, GA, HA (A, B, C, D) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 1137 (UniProt: A0A2A9IR05)
| PDB | External Database | Details |
|---|---|---|
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 1055 | Thr 1055 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 509398.3 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 7030.4 | |
| All* | Total formula weight | 516428.7 |
