7ZZ8
Cryo-EM structure of Lactococcus lactis pyruvate carboxylase with acetyl-CoA and cyclic di-AMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyruvate carboxylase | polymer | 1143 | 127349.6 | 4 | UniProt (A0A2A9IR05) | Lactococcus lactis | |
| 2 | BA, E, H, L, O... (D, A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) PubChem (888) | |||
| 3 | F, M, T, Z (A, B, C, D) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) PubChem (27854) | |||
| 4 | AA, G, N, U (D, A, B, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
| 5 | CA, I, P, W (D, A, B, C) | ACETYL COENZYME *A | non-polymer | 809.6 | 4 | Chemie (ACO) PubChem (25210474) PubChem (24860528) PubChem (53393727) PubChem (56846401) PubChem (44141873) PubChem (45254004) PubChem (444493) PubChem (53245716) PubChem (87656764) PubChem (181) PubChem (6302) PubChem (87656765) PubChem (89102998) PubChem (91746285) PubChem (6857822) PubChem (6917106) PubChem (134956084) PubChem (10079099) PubChem (124511019) PubChem (11987898) PubChem (16061174) PubChem (124931617) PubChem (129274027) PubChem (154496096) PubChem (162968672) PubChem (170108977) | |||
| 6 | DA, J, Q, X (D, A, B, C) | PYRUVIC ACID | non-polymer | 88.1 | 4 | Chemie (PYR) PubChem (1060) | |||
| 7 | K, R (A, C) | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide | non-polymer | 658.4 | 2 | Chemie (2BA) | |||
| 8 | EA, FA, GA, HA (A, B, C, D) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 1137 (UniProt: A0A2A9IR05)
| PDB | External Database | Details |
|---|---|---|
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 1055 | Thr 1055 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 509398.3 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 7030.4 | |
| All* | Total formula weight | 516428.7 |
