7ZYW
Crystal structure of T2R-TTL-PM534 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 2 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) In PDB | Bos taurus (cattle) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B, D | Tubulin beta-2B chain | polymer | 445 | 49999.9 | 2 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) In PDB | Bos taurus (cattle) | |
| 3 | E | Stathmin-4 | polymer | 189 | 22125.3 | 1 | UniProt (P63043) Pfam (PF00836) In PDB | Rattus norvegicus (Norway rat) | Stathmin-like protein B3,RB3 |
| 4 | F | Tubulin beta-2B chain | polymer | 384 | 44378.5 | 1 | UniProt (E1BQ43) Pfam (PF03133) UniProt (by SIFTS) (A0A8V0Z8P0) In PDB | Gallus gallus (chicken) | |
| 5 | A, C | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 6 | A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 7 | A, B, C | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 8 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 9 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 10 | B, D | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 11 | B | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 12 | B, D | (4R)-N-[(1R)-1-[4-(cyclopropylmethoxy)-6-oxidanylidene-pyran-2-yl]butyl]-4-methyl-2-[(E)-C-methyl-N-oxidanyl-carbonimidoyl]-5H-1,3-thiazole-4-carboxamide | non-polymer | 421.5 | 2 | Chemie (KG0) | |||
| 13 | C | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 14 | F | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) | |||
| 15 | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence modifications
F: 1 - 378 (UniProt: E1BQ43)
| PDB | External Database | Details |
|---|---|---|
| His 379 | - | expression tag |
| His 380 | - | expression tag |
| His 381 | - | expression tag |
| His 382 | - | expression tag |
| His 383 | - | expression tag |
| His 384 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 266912.5 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 4175.6 | |
| All* | Total formula weight | 271088.1 |
