7ZXW
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with the 5-[(morpholin-4-yl)methyl]quinolin-8-ol inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-glucose-glycoprotein glucosyltransferase-like protein | polymer | 295 | 35056.9 | 1 | UniProt (G0SB58) Pfam (PF18404) | Thermochaetoides thermophila DSM 1495 | |
| 2 | B (B) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 3 | C (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D (A) | URIDINE-5'-DIPHOSPHATE-GLUCOSE | non-polymer | 566.3 | 1 | Chemie (UPG) | |||
| 5 | E, G, H, I, J (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 5 | Chemie (DMS) | |||
| 6 | F (A) | 5-(morpholin-4-ylmethyl)quinolin-8-ol | non-polymer | 244.3 | 1 | Chemie (JM3) | |||
| 7 | K (A) | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence modifications
A: 1191 - 1473 (UniProt: G0SB58)
| PDB | External Database | Details |
|---|---|---|
| Glu 1188 | - | expression tag |
| Thr 1189 | - | expression tag |
| Gly 1190 | - | expression tag |
| Gly 1474 | - | expression tag |
| Thr 1475 | - | expression tag |
| Lys 1476 | - | expression tag |
| His 1477 | - | expression tag |
| His 1478 | - | expression tag |
| His 1479 | - | expression tag |
| His 1480 | - | expression tag |
| His 1481 | - | expression tag |
| His 1482 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35056.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1241.3 | |
| All* | Total formula weight | 36884.8 |
