7ZWP
Crystal structure of human BCL6 BTB domain in complex with compound 7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | B-cell lymphoma 6 protein | polymer | 128 | 14536.9 | 1 | UniProt (P41182) Pfam (PF00651) | Homo sapiens (human) | BCL-6,B-cell lymphoma 5 protein,BCL-5,Protein LAZ-3,Zinc finger and BTB domain-containing protein 27,Zinc finger protein 51 |
| 2 | B (B) | ALA-TRP-VAL-ILE-PRO-ALA | polymer | 6 | 655.8 | 1 | synthetic construct | ||
| 3 | C (A) | ethyl 5-propyl-7-pyridin-4-yl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate | non-polymer | 311.3 | 1 | Chemie (K4C) | |||
| 4 | D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A: 5 - 129 (UniProt: P41182)
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | - | expression tag |
| Pro 3 | - | expression tag |
| Gly 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 15192.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 435.5 | |
| All* | Total formula weight | 15628.2 |
