7ZV3
Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0472
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Indoleamine 2,3-dioxygenase 1 | polymer | 423 | 47504.5 | 2 | UniProt (P14902) Pfam (PF01231) In PDB | Homo sapiens (human) | IDO-1,Indoleamine-pyrrole 2,3-dioxygenase |
2 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
3 | A, B | 4-(3-chloro-2-phenethylphenyl)-1H-1,2,3-triazole | non-polymer | 283.8 | 2 | Chemie (RCT) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
6 | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 403 (UniProt: P14902)
PDB | External Database | Details |
---|---|---|
Met -19 | - | initiating methionine |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Ser 3 | His 3 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 95009.0 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 2084.7 | |
All* | Total formula weight | 97093.7 |