7ZTX
Crystal structure of mutant AR-LBD (F755V) bound to dihydrotestosterone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 249 | 28998.0 | 1 | UniProt (P10275) Pfam (PF00104) | Homo sapiens (human) | Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
| 2 | B (A) | 5-ALPHA-DIHYDROTESTOSTERONE | non-polymer | 290.4 | 1 | Chemie (DHT) PubChem (16395945) PubChem (1779160) PubChem (23729584) PubChem (44264584) PubChem (44307156) PubChem (44308180) PubChem (44314545) PubChem (1779165) PubChem (1779163) PubChem (44403751) PubChem (54132599) PubChem (57253355) PubChem (2748143) PubChem (11302) PubChem (968803) PubChem (6951009) PubChem (124916763) PubChem (67080676) PubChem (68213431) PubChem (70627790) PubChem (133612463) PubChem (11869360) PubChem (15) PubChem (76333143) PubChem (10635) PubChem (90350225) PubChem (147320) PubChem (16111632) PubChem (667503) PubChem (928651) PubChem (124305346) PubChem (124335861) PubChem (124350819) PubChem (124362930) PubChem (124402106) PubChem (124420348) PubChem (124907326) PubChem (124907327) PubChem (6432518) PubChem (7052570) PubChem (7052571) PubChem (9965809) PubChem (134753818) PubChem (10379482) PubChem (10902374) PubChem (11860392) PubChem (11867857) PubChem (11867858) PubChem (11867859) PubChem (11867860) PubChem (11869358) PubChem (11869359) PubChem (11869361) PubChem (11914201) PubChem (11920866) PubChem (139564330) PubChem (141909893) PubChem (142776876) PubChem (145087815) PubChem (12446746) PubChem (12446747) PubChem (12446748) PubChem (12446749) PubChem (12446752) PubChem (156740897) PubChem (162854571) PubChem (162854572) PubChem (162854573) PubChem (164663566) PubChem (165146196) PubChem (165431280) | |||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 5 | F (A) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A: 672 - 920 (UniProt: P10275)
| PDB | External Database | Details |
|---|---|---|
| Val 755 | Phe 755 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28998.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 551.7 | |
| All* | Total formula weight | 29549.7 |
